ISSN 2304-1226 (Print)

List of issues > Series «Psychology». 2020. Vol. 31

Placebo Phenomenon as a Promising Direction of Psychological and Physiological Studies

O. G. Kenunen, N. P. Rebrova

A placebo phenomenon, though being widely known, is currently not the subject of research of Russian scientists, and common perception of it does not conform to current academic thinking. The paper presents the relevant information concerning the phenomenon. The analysis results lead to a conclusion that a placebo effect goes far beyond traditionally prescribed therapeutic use. The study of this phenomenon contributes to better understanding of the nature of psychical function and is beneficial for professionals of various fields including psychologists and educators. Latest studies make it necessary for new conceptualization of the phenomenon. The paper for the first time puts forward the idea to treat a placebo phenomenon in terms of the theory of functional systems. This offers prospects for psychological research in the direction not being developed in our country.

About the Authors

Kenunen Olga Gennadevna, Candidate of Sciences (Biology), Associate Professor, Department of Clinical Psychology and Psychological Help, Herzen State Pedagogical University of Russia, 48, Moika River Embankment, St.-Petersburg, 191186, Russian Federation, e-mail O_Kenunen@mail.ru 

Rebrova Nina Pavlovna, Candidate of Sciences (Biology), Associate Professor, Department of Clinical Psychology and Psychological Help, Herzen State Pedagogical University of Russia, 48, Moika River Embankment, St.-Petersburg, 191186, Russian Federation, e-mail: nina.rebrova@gmail.com

For citation

Kenunen O.G., Rebrova N.P. Placebo Phenomenon as a Promising Direction of Psychological and Physiological Studies. The Bulletin of Irkutsk State University. Series Psychology, 2020, vol. 31, pp. 30-42. https://doi.org/10.26516/2304-1226.2020.31.30 (in Russian)

placebo effect, nocebo effect, anxiety, learning, functional systems

Aleksandrov Yu. Vvedenie v sistemnuyu psikhofiziologiyu [Introduction to systemic psychophysiology]. Psikhologiya XXI veka [Psychology of the 21st Century]. Moscow, PER SE. Publ., 2003, pp. 39-85. (In Russian)

Anokhin P.K. Uzlovye voprosy teorii funktsionalnoi sistemy [Nodal questions of the theory of a functional system]. Moscow, Nauka Publ., 1980, 196 p. (In Russian)

Kenunen O. Pamyati Izyaslava Petrovicha Lapina. Neskolko slov o fenomene platsebo [In memory of Izyaslav Petrovich Lapin. A few words about the placebo phenomenon]. Med. psihol. Ross. [Medical Psychology in Russia], 2013, no. 4 (21). Available at: http://mprj.ru (date of access: 27.10.2019). (In Russian)

Lapin I.P. Platsebo i terapiya [Placebo and therapy]. Saint-Petersburg, Lan Publ., 2000, 223 p. (In Russian)

Tuchina D. [et al.]. Primenenie effekta platsebo v psikhoterapii narkologicheskikh bolnykh: terapevticheskie i eticheskie aspekty. [The practical use of placebo effect in psychotherapeutic treatment of patients with substance use disorders: therapeutic and ethic consequences]. Zhurnal neurologii i psikhiatrii imeni S.S. Korsakova [S.S. Korsakov Journal of Neurology and Psychiatry], 2016, no. 11 (2), pp. 61-68 (In Russian)

Sokolova L.V. A.A. Ukhtomskii i kompleksnaya nauka o cheloveke [Ukhtomsky and the complex science of man]. Saint-Petersburg, S.-Pererb. Univ. Publ., 2010, 316 p. (In Russian)

Sudakov K. (Ed.). Funktsionalnye sistemy organizma [The functional systems of the body]. Moscow, Meditsina Publ., 1987, 432 p. (In Russian)

Frit K. Mozg i dusha: Kak nervnaya deyatelnost formiruet nash vnutrennii mir [Making Up The Mind: How the Brain Creates our Mental World]. Moscow, Astrel Publ., Corpus Publ., 2010, 335 p. (In Russian)

Khailov P. Platsebo i dokazatelnaya meditsina [Placebo and Evidence-Based Medicine]. Meditsinskie tekhnologii. Otsenka i vybor [Medical technologiesAssesment and choice], 2012, no. 1, pp. 10-16 (In Russian)

Hart Y. et al. Automated Video Analysis of Non-verbal Communication in a Medical Setting. Front. Psychol, 2016, no. 7, pp. 1130. https://doi.org/10.3389/fpsyg.2016.01130

Benedetti F. No prefrontal control, no placebo response. PAIN, 2010, no. 148 (3), pp. 357‒358

Benedetti F. Placebo-Induced Improvements: How Therapeutic Rituals Affect the Patient's Brain. J Acupunct Meridian Stud, 2012, no. 5 (3), pp. 97-103

Benedetti F. Placebo Effects: From the Neurobiological Paradigm to Translational Implications. Neuron, 2014, no. 84. pp. 623-637. https://doi.org/10.1038/nrn3976.

Benedetti F., Piedimonte A., Frisaldi E. How do placebos work? Eur J Psychotraumatol, 2018, no. 9, pp. 1533370. https://doi.org/10.1080/20008198.2018.1533370

Kaptchuk T.J. et al. Components of placebo effect: randomised controlled trial in patients with irritable bowel syndrome. BMJ, 2008, no. 336 (7651), pp. 999 -1003

Corsi N., Colloca L. Placebo and Nocebo Effects: The Advantage of Measuring Expectations and Psychological Factors. Front Psychol, 2017, no. 8, pp. 308. https://doi.org/10.3389/fpsyg.2017.00308

Grahl A., Onat S., Büchel C. The periaqueductal gray and Bayesian integration in placebo analgesia. Elife, 2018, no. 7, pp. 32930. https://doi.org/10.7554/eLife.32930

Levine J.D, Gordon N.C, Fields H.L. The mechanism of placebo analgesia. Lancet, 1978, no. 2 (8091), pp. 654-657.

Finniss D.G. et al. Placebo Effects: Biological, Clinical and Ethical Advances. Lancet, 2010, no. 375 (9715), pp. 686‒695

Rosenthal R., Jacobson L. Pygmalion in the classroom. Urban Rev, 1968, no. 3, pp. 16. https://doi.org/10.1007/BF02322211

Silberman S. Placebos Are Getting More Effective. Drugmakers Are Desperate to Know Why. Wired, 2009, no. 17 (9). Available at: http://www.wired.com/medtech/drugs/magazine/17-09/ff_placebo_effect?currentPage=all (date of access: 05.03.2019).

Wager T.D., Atlas L.Y. The neuroscience of placebo effects: connecting context, learning and health. Nat Rev Neurosci, 2015, no. 16 (7), pp. 403‒418. https://doi.org/10.1038/nrn3976

Benedetti F., Lanotte M., Lopiano L., Colloca L. When words are painful: Unraveling the mechanisms of the nocebo effect. Neuroscience, 2007, no. 147 (2), pp. 260‒271 

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